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1

Melatonin osteoporosis prevention study (MOPS): a randomized, double-blind, placebo-controlled study examining the effects of melatonin on bone health and quality of life in perimenopausal women

Mary P. Kotlarczyk, Holly C. Lassila, Christine K. O’Neil, Frank D’Amico, Larry T. Enderby, Paula A. Witt-Enderby, Judith L. Balk

Journal:

Journal of Pineal Research

Year:

2012

Language:

english

File:

PDF, 475 KB

english, 2012

2

Melatonin-micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal osteopenic women following a one-year double-blind RCT and on osteoblast-osteoclast co-cultures

Maria, Sifat, Swanson, Mark H., Enderby, Larry T., D’Amico, Frank, Enderby, Brianna, Samsonraj, Rebekah M., Dudakovic, Amel, van Wijnen, Andre J., Witt-Enderby, Paula A.

Journal:

Year:

2017

Language:

english

File:

PDF, 3.35 MB

english, 2017

3

Modulation of melatonin receptors and G-protein function by microtubules

Michael J. Jarzynka, Deepshikha K. Passey, Paul F. Ignatius, Melissa A. Melan, Nicholas M. Radio, Ralf Jockers, Mark M. Rasenick, Lena Brydon, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2006

Language:

english

File:

PDF, 541 KB

english, 2006

4

Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures

Maria, Sifat, Witt-Enderby, Paula A.

Journal:

Journal of Pineal Research

Year:

2014

Language:

english

File:

PDF, 458 KB

english, 2014

5

Platelet-Rich Preparations to Improve Healing. Part II: Platelet Activation and Enrichment, Leukocyte Inclusion, and Other Selection Criteria

Davis, Vicki L, Abukabda, Alaeddin B, Radio, Nicholas M, Witt-Enderby, Paula A, Clafshenkel, William P, Cairone, J. Vito, Rutkowski, James L

Journal:

Journal of Oral Implantology

Year:

2014

Language:

english

File:

PDF, 89 KB

english, 2014

6

Platelet-Rich Preparations to Improve Healing. Part I: Workable Options for Every Size Practice

Davis, Vicki L, Abukabda, Alaeddin B, Radio, Nicholas M, Witt-Enderby, Paula A, Clafshenkel, William P, Cairone, J. Vito, Rutkowski, James L

Journal:

Journal of Oral Implantology

Year:

2014

Language:

english

File:

PDF, 354 KB

english, 2014

7

Melatonin and breast cancer: cellular mechanisms, clinical studies and future perspectives

Grant, Stephen G., Melan, Melissa A., Latimer, Jean J., Witt-Enderby, Paula A.

Journal:

Expert Reviews in Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 250 KB

english, 2009

8

The Effect of Melatonin Upon Postacute Withdrawal Among Males in a Residential Treatment Program (M-PAWS)

Bondi, Corry D., Kamal, Khalid M., Johnson, David A., Witt-Enderby, Paula A., Giannetti, Vincent J.

Journal:

Journal of Addiction Medicine

Year:

2018

Language:

english

File:

PDF, 205 KB

english, 2018

9

Melatonin induction of filamentous structures in non-neuronal cells that is dependent on expression of the human mt1 melatonin receptor

Paula A. Witt-Enderby, Renee S. MacKenzie, Raelene M. McKeon, Elizabeth A. Carroll, Shannon L. Bordt, Melissa A. Melan

Journal:

Year:

2000

Language:

english

File:

PDF, 422 KB

english, 2000

10

N-Acetyl-5-arylalkoxytryptamine Analogs: Probing the Melatonin Receptors for MT1-Selectivity

Christian Markl, William P. Clafshenkel, Mohamed I. Attia, Shalini Sethi, Paula A. Witt-Enderby, Darius P. Zlotos

Journal:

Archiv der Pharmazie

Year:

2011

Language:

english

File:

PDF, 306 KB

english, 2011

11

ChemInform Abstract: Synthesis and Pharmacological Analysis of High Affinity Melatonin Receptor Ligands.

Guo-Hua Chu, Paula A. Witt-Enderby, Marla Jones, Pui-Kai Li

Journal:

Year:

2002

File:

PDF, 31 KB

2002

12

Synthesis and pharmacological evaluation of pentacyclic 6a,7-dihydrodiindole and 2,3-dihydrodiindole derivatives as novel melatoninergic ligands

Mohamed I. Attia, Paula A. Witt-Enderby, Justin Julius

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 287 KB

english, 2008

13

Synthesis and pharmacological evaluation of 6a,7-dihydro-6H,13H-pyrazino[1,2-a;4,5-a′]diindole analogs as melatonin receptor ligands

Mohamed I. Attia, Justin Julius, Paula A. Witt-Enderby, Darius P. Zlotos

Journal:

Year:

2007

Language:

english

File:

PDF, 238 KB

english, 2007

14

Synthesis and receptor binding studies of quinolinic derivatives as melatonin receptor ligands

Pui-Kai Li, Guo-Hua Chu, Megan L. Gillen, Paula A. Witt-Enderby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 185 KB

english, 1997

15

The development of a charged melatonin receptor ligand

Pui-Kai Li, Guo-Hua Chu, Megan L. Gillen, Tejal Parekh, Paula A. Witt-Enderby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 223 KB

english, 1997

16

Synthesis and pharmacological evaluation of 1,2,3,4-tetrahydropyrazino[1,2-a]indole and 2-[(phenylmethylamino)methyl]-1H-indole analogues as novel melatoninergic ligands

Christian Markl, Mohamed I. Attia, Justin Julius, Shalini Sethi, Paula A. Witt-Enderby, Darius P. Zlotos

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 446 KB

english, 2009

17

Melatonin enhances alkaline phosphatase activity in differentiating human adult mesenchymal stem cells grown in osteogenic medium via MT2 melatonin receptors and the MEK/ERK (1/2) signaling cascade

Nicholas M. Radio, John S. Doctor, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2006

Language:

english

File:

PDF, 304 KB

english, 2006

18

Therapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapy

Paula A. Witt-Enderby, Nicholas M. Radio, John S. Doctor, Vicki L. Davis

Journal:

Journal of Pineal Research

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

19

C-terminal domains within human MT1 and MT2 melatonin receptors are involved in internalization processes

Shalini Sethi, Wendy Adams, John Pollock, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2008

Language:

english

File:

PDF, 327 KB

english, 2008

20

MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation

C. Dominic Bondi, Raelene M. McKeon, Jennifer M. Bennett, Paul F. Ignatius, Lena Brydon, Ralf Jockers, Melissa A. Melan, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2008

Language:

english

File:

PDF, 386 KB

english, 2008

21

Microtubules modulate melatonin receptors involved in phase-shifting circadian activity rhythms: in vitro and in vivo evidence

Michael J. Jarzynka, Deepshikha K. Passey, David A. Johnson, Nagarjun V. Konduru, Nicholas F. Fitz, Nicholas M. Radio, Mark Rasenick, Susan Benloucif, Melissa A. Melan, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2009

Language:

english

File:

PDF, 405 KB

english, 2009

22

Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways

Shalini Sethi, Nicholas M. Radio, Mary P. Kotlarczyk, Chien-Tsun Chen, Yau-Huei Wei, Ralf Jockers, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2010

Language:

english

File:

PDF, 717 KB

english, 2010

23

Dual coupling of MT1 and MT2 melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure

Renee S MacKenzie, Melissa A Melan, Deepshikha K Passey, Paula A Witt-Enderby

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 243 KB

english, 2002

24

Melatonin differentially modulates the expression and function of the hMT1 and hMT2 melatonin receptors upon prolonged withdrawal

Monica I. Masana, Paula A. Witt-Enderby, Margarita L. Dubocovich

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 267 KB

english, 2003

25

Effects on bone by the light/dark cycle and chronic treatment with melatonin and/or hormone replacement therapy in intact female mice

Paula A. Witt-Enderby, John P. Slater, Nakpangi A. Johnson, Corry D. Bondi, Balasunder R. Dodda, Mary P. Kotlarczyk, William P. Clafshenkel, Shalini Sethi, Suzanne Higginbotham, James L. Rutkowski, Ka

Journal:

Journal of Pineal Research

Year:

2012

Language:

english

File:

PDF, 367 KB

english, 2012

26

A novel calcium aluminate-melatonin scaffold enhances bone regeneration within a calvarial defect

William P. Clafshenkel, James L. Rutkowski, Rachelle N. Palchesko, Jared D. Romeo, Ken A. McGowan, Ellen S. Gawalt, Paula A. Witt-Enderby

Journal:

Journal of Pineal Research

Year:

2012

Language:

english

File:

PDF, 608 KB

english, 2012

27

Chronic exposure to a β2-adrenoceptor agonist increases the airway response to methacholine

Paula A. Witt-Enderby, Henry I. Yamamura, Marilyn Halonen, John D. Palmer, John W. Bloom

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 244 KB

english, 1993

28

The actions of a charged melatonin receptor ligand, TMEPI, and an irreversible MT2 receptor agonist, BMNEP, on mouse hippocampal evoked potentials in vitro

Yasir El-Sherif, Paula Witt-Enderby, Pui-Kai Li, Jene Tesoriero, Michael V. Hogan, Andrzej Wieraszko

Journal:

Year:

2004

Language:

english

File:

PDF, 159 KB

english, 2004

29

Corrigendum to “The actions of a charged melatonin receptor ligand, TMEPI, and an irreversible MT2 receptor agonist, BMNEP, on mouse hippocampal evoked potentials in vitro”: [Life Sciences 75 (2004) 3147–3156]

Yasir El-Sherif, Paula Witt-Enderby, Pui-Kai Li, Jene Tesoriero, Michael V. Hogan, Andrzej Wieraszko

Journal:

Year:

2005

Language:

english

File:

PDF, 47 KB

english, 2005

30

Melatonin receptors and their regulation: biochemical and structural mechanisms

Paula A Witt-Enderby, Jennifer Bennett, Michael J Jarzynka, Steven Firestine, Melissa A Melan

Journal:

Year:

2003

Language:

english

File:

PDF, 445 KB

english, 2003

31

N1E-115 mouse neuroblastoma cells express mt1 melatonin receptors and produce neurites in response to melatonin

Shannon L. Bordt, Raelene M. McKeon, Pui-Kai Li, Paula A. Witt-Enderby, Melissa A. Melan

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2001

Language:

english

File:

PDF, 348 KB

english, 2001

32

Melatonin decreases cell proliferation and transformation in a melatonin receptor-dependent manner

Marla P Jones, Melissa A Melan, Paula A Witt-Enderby

Journal:

Year:

2000

Language:

english

File:

PDF, 331 KB

english, 2000

33

Synthesis, NMR conformational analysis and pharmacological evaluation of 7,7a,13,14-tetrahydro-6H-cyclobuta[b]pyrimido[1,2-a:3,4-a?]diindole analogues as melatonin receptor ligands

Attia, Mohamed I., G?cl?, Deniz, Hertlein, Barbara, Julius, Justin, Witt-Enderby, Paula A., Zlotos, Darius P.

Journal:

Organic & Biomolecular Chemistry

Year:

2007

Language:

english

File:

PDF, 275 KB

english, 2007

34

Could the Fountain of Youth Be All in Your Bones?

Witt-Enderby, Paula A.

Journal:

Journal of Oral Implantology

Year:

2013

Language:

english

File:

PDF, 28 KB

english, 2013

35

Platelet-Rich Preparations to Improve Healing. Part II: Platelet Activation and Enrichment, Leukocyte Inclusion, and Other Selection Criteria

Davis, Vicki L., Abukabda, Alaeddin B., Radio, Nicholas M., Witt-Enderby, Paula A., Clafshenkel, William P., Cairone, J Vito, Rutkowski, James L.

Journal:

Journal of Oral Implantology

Year:

2012

Language:

english

File:

PDF, 573 KB

english, 2012

36

Platelet-Rich Preparations to Improve Healing. Part I: Workable Options for Every Size Practice

Davis, Vicki L., Abukabda, Alaeddin B., Radio, Nicholas M., Witt-Enderby, Paula A., Clafshenkel, William P., Cairone, J Vito, Rutkowski, James L.

Journal:

Journal of Oral Implantology

Year:

2012

Language:

english

File:

PDF, 588 KB

english, 2012

37

High affinity nuclear and nongenomic estradiol binding sites in the human and mouse lens

Kirker, M. Rachel, Gallagher, Katie M., Witt-Enderby, Paula A., Davis, Vicki L.

Journal:

Experimental Eye Research

Year:

2013

Language:

english

File:

PDF, 924 KB

english, 2013

38

2-[(1,3-Dihydro-2H-isoindol-2-yl)methyl]melatonin – a novel MT2-selective melatonin receptor antagonist

Heckman, David, Attia, Mohamed I., Behnam, Mira A. M., Mohsen, Amal M. Y., Markl, Christian, Julius, Justin, Sethi, Shalini, Witt-Enderby, Paula A., Zlotos, Darius P.

Journal:

Year:

2011

Language:

english

File:

PDF, 152 KB

english, 2011

39

MT 1 and MT 2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential

Zlotos, Darius. P., Jockers, Ralf, Cecon, Erika, Rivara, Silvia, Witt-Enderby, Paula A.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.97 MB

english, 2014

40

2-[(2,3-Dihydro-1 H -indol-1-yl)methyl]melatonin Analogues: A Novel Class of MT 2 -Selective Melatonin Receptor Antagonists

Zlotos, Darius P., Attia, Mohamed I., Julius, Justin, Sethi, Shalini, Witt-Enderby, Paula A.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 307 KB

english, 2009

41

Development of a High-Affinity Ligand That Binds Irreversibly to Mel 1b Melatonin Receptors

Witt-Enderby, Paula A., Chu, Guo-Hua, Gillen, Megan L., Li, Pui-Kai

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 186 KB

english, 1997

42

N1-linked melatonin dimers as bivalent ligands targeting dimeric melatonin receptors

Journé, Anne-Sophie, Habib, Samy A. M., Dodda, Bala R., Morcos, Mina N. F., Sadek, Mirna S., Tadros, Sarah A. A., Witt-Enderby, Paula A., Jockers, Ralf, Zlotos, Darius P.

Journal:

Year:

2014

Language:

english

File:

PDF, 423 KB

english, 2014

43

Morinda citrifolia (Noni) Juice Augments Mammary Gland Differentiation and Reduces Mammary Tumor Growth in Mice Expressing the Unactivated c- erb B2 Transgene

Clafshenkel, William P., King, Tracy L., Kotlarczyk, Mary P., Cline, J. Mark, Foster, Warren G., Davis, Vicki L., Witt-Enderby, Paula A.

Journal:

Evidence-based Complementary and Alternative Medicine

Year:

2012

Language:

english

File:

PDF, 2.20 MB

english, 2012

44

Novel difluoroacetamide analogues of agomelatine and melatonin: probing the melatonin receptors for MT 1 selectivity

Zlotos, Darius P., Riad, Noura M., Osman, Mai B., Dodda, Bala R., Witt-Enderby, Paula A.

Journal:

Year:

2015

Language:

english

File:

PDF, 217 KB

english, 2015

45

Physiological Exposure to Melatonin Supersensitizes the Cyclic Adenosine 3′,5′-Monophosphate-Dependent Signal Transduction Cascade in Chinese Hamster Ovary Cells Expressing the Human mt 1 Melatonin Receptor 1

Witt-Enderby, Paula A., Masana, Monica I., Dubocovich, Margarita L.

Journal:

Year:

1998

Language:

english

File:

PDF, 311 KB

english, 1998

46

Synthesis and Pharmacological Analysis of High Affinity Melatonin Receptor Ligands

Chu, Guo-Hua, Witt-Enderby, Paula A., Jones, Marla, Li, Pui-Kai

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2002

Language:

english

File:

PDF, 58 KB

english, 2002

47

[Vitamins & Hormones] Volume 58 || Melatonin receptors and ligands

Witt-Enderby, Paula A.

Year:

2000

Language:

english

File:

PDF, 3.51 MB

english, 2000

48

Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration

Hasan, Mahmud, Genovese, Salvatore, Fiorito, Serena, Epifano, Francesco, Witt-Enderby, Paula A.

Journal:

Journal of Natural Products

Year:

2017

Language:

english

File:

PDF, 3.43 MB

english, 2017

49

Relationship between melatonin and bone resorption rhythms in premenopausal women

St Hilaire, Melissa A., Rahman, Shadab A., Gooley, Joshua J., Witt-Enderby, Paula A., Lockley, Steven W.

Journal:

Journal of Bone and Mineral Metabolism

Year:

2018

Language:

english

File:

PDF, 1.80 MB

english, 2018

50

The Impact of Hormonal Contraceptives on Breast Cancer Pathology

Dorchak, Jesse A., Maria, Sifat, Guarinoni, Joseph L., Duensing, Anette, Somiari, Stella, Cavanaugh, Jane, Deyarmin, Brenda, Hu, Hai, Iida, Joji, Shriver, Craig D., Witt-Enderby, Paula A.

Journal:

Hormones and Cancer

Year:

2018

Language:

english

File:

PDF, 600 KB

english, 2018

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